AmaZulu and Kaizer Chiefs played to a goalless draw at the King Zwelithini Stadium in Durban.
The draw takes Usuthu to ninth spot on the league standings, while Amakhosi climb up to sixth place on the table.
The match got off to a lively start with Usuthu applying some pressure on the Amakhosi defence.
Chiefs keeper Itumeleng Khune produced two good saves to deny AmaZulu duo Rhulani Manzini and Siyethemba Mnguni within two minutes.
Manzini unleashed a long-range shot which was saved by Khune, who then made a great save to deny Mnguni from close range.
Amakhosi had a rare chance in the 26th minute following a scramble in the Usuthu box and Philani Zulu fired over the crossbar from close range.
The hosts were unfortunate not to break the deadlock 12 minutes later as AmaZulu piled more pressure on Chiefs.
Khune saved Mbongeni Gumede’s effort, before the Chiefs shot-stopper denied Phumlani Gumede from the rebound.
Amazulu were awarded a penalty a few minutes into the second half, but was denied by Khune from the spot-kick.
AmaZulu goalkeeper Boalefa Pule was finally seriously tested in the 66th minute when he made a good reaction save to deny Chiefs striker Gustavo Paez.
Chiefs pushed for a late winning goal and Pule pulled off a good save to deny Parker with time running out.
Phumlani Gumede, the Usuthu defender, was sent off in the 89th minute, but AmaZulu stood firm at the back and the match ended in a goalless draw.
In North West, Bloemfontein Celtic bagged a vital point on the road as they drew 0-0 against Platinum Stars in the Absa Premiership at the Royal Bafokeng Stadium in Rustenburg on Wednesday night.
Following the stalemate, Phunya Sele Sele moves to fourth spot with 16 points from 11 games.
Meanwhile, Maritzburg United held Polokwane City to a 0-0 draw in an Absa Premiership clash at the Old Peter Mokaba Stadium in Polokwane on Wednesday evening.
Neither side was able to find the back of the net in what was an uneventful clash, with the result and performance leaving the two sides with a lot to ponder.
A point takes Rise and Shine up to 11th on the log standings, while the Team of Choice remain in 13th, in what has been a barren run for the KwaZulu-Natal outfit.