Mamelodi Sundowns needs to win their match against Wydad Casablanca, to strengthen their chances of qualifying for the CAF Championship knockout stage.
If they lose against the hosts at Stade Mohammed V in Casablanca, Morocco Wydad will qualify with a match to spare, leaving Sundowns and Horoya in Group C to fight it out for the second spot.
The match starts at 9pm South African time.
Only two teams are set to qualify for the knockout stages from each group. Casablanca leads Group C with eight points after four matches.
They are followed by Sundowns, with Horoya in third place. Both have five points, but Sundowns are ahead on goal difference. Togo-Port who are fourth placed with three points cannot be ruled out of the competition. They could qualify if they win both their remaining matches.
Sundowns coach, Pitso Mosimane, says managing his team ahead of the Wydad encounter has been the key.