Wits finished the match with 10 men after stalwart defender Buhle Mkhwanazi was sent off for a second bookable offence.
Sundowns attacking midfielder Sibusiso Vilakazi was unlucky not to break the deadlock, when his effort shaved the upright in the second half.
Sundowns coach Pitso Mosimane was not happy with referee Abongile Tom.
The Brazilians also had a penalty shout in the second half when a ball from Vilakazi appeared to hit one of the defender’s hand in the second half, but the referee waved play on.
The Premier Soccer League (PSL) champions are still second on the log with 32 points in 16 matches, three points off log leaders Kaizer Chiefs.
Mosimane was not unhappy with the results. He says he was not sure about the penalty call.
The two teams played to a 1-1 draw in Durban last month. Wits are lying third on the log with 27 points in 13 matches.
Wits coach Gavin Hunt was disappointed they did not get maximum points despite finishing the match with 10 men.
Sundowns and Wits are involved in the group stages of both the CAF Champions League and CAF Confederation Cup respectively.
The two teams will be involved in the CAF games this weekend. Hunt says playing too many games in a short space of time had a bearing on the game.
– Report by Vincent Sitsula
— Mamelodi Sundowns FC (@Masandawana) January 8, 2020