Namibia will suspend its rollout of Russia’s Sputnik V COVID-19 vaccine, its health ministry said on Saturday, days after the drugs regulator in neighbouring South Africa flagged concerns about its safety for people at risk of HIV.
The Gamaleya Research Institute, which developed Sputnik V, said Namibia’s decision was not based on any scientific evidence or research.
The South African Health Products Regulatory Authority (SAHPRA) decided not to approve an emergency use application for Sputnik V for now because, it said, some studies suggested that administration of vaccines using the Adenovirus Type 5 vector – which Sputnik V does – was associated with higher susceptibility to HIV in men.
Namibia’s health ministry said in a statement that the decision to discontinue use of the Russian vaccine was “out of (an) abundance of caution that men (who) received Sputnik V may be at higher risk of contracting HIV,” adding that it had taken SAHPRA’s decision into account.
Sputnik V remains one of the safest and most efficient vaccines against COVID-19 in use globally, the Gamaleya institute told Reuters. It said more than 250 clinical trials and 75 international publications confirmed the safety of vaccines and medicines based on human adenovirus vectors.
“While adenoviruses, including ad-5, are one of the most frequent causes of light common flu…, there is no evidence of increased risk of HIV infection among human population after (the) common cold,” the institute said.
A meta-analysis of six clinical studies and their long-term follow-up in 7,092 participants showed there was no statistically significant increase of HIV-1 infection among adenovirus type-5 vectored vaccine recipients, it said.