Health Minister Aaron Motsoaledi has described the scenes at the Charlotte Maxeke hospital as hooliganism.
This follows protest action by general workers that saw 31 medical operations disrupted and patients sent away.
The workers are unhappy over unpaid bonuses and are demanding an increase of 12%.
It is the second strike in two months; this time the protest is over alleged promises by the Health department.
Doctors were disrupted from their duties and medical theatres were thrashed.
Motsoaledi says the actions of the protestors were unjustifiable.
It is unclear what action will be taken against those involved in the strike.
But the thousands of patients at the hospital hope the Minister’s intervention will avert further disruptions.