The number of confirmed coronavirus cases in Germany jumped by more than 100 on Saturday, reaching 795 by mid-afternoon amid growing concern at the economic impact of the spreading epidemic on one of the world’s most trade-dependent economies.

The number recorded by the Robert Koch Institute stood at 684 in the morning, with large clusters in the west and south, where an initial outbreak centered on a car supplier with a unit in Wuhan, where the infection was first detected.

The total is well over 10 times larger than it was a week ago. There were 66 cases on February 29.

Western Europe’s most populous country has the second largest number of registered cases on the continent after Italy.

So far, no deaths have been reported, though the RND newspaper group reported that a transplant patient with a depressed immune system who had contracted coronavirus was in a critical condition.

With concern growing at the vulnerability of long international supply chains to such an epidemic, Ola Kallenius, chief executive of Mercedes maker Daimler , warned against a return to economic nationalism.